Yintoni iUrticaria?
I-Urticaria sisifo esiqhelekileyo. Inokwenzeka nakweyiphi na iminyaka, ukusuka ebusaneni ukuya ebudaleni. Amashumi amabini anesihlanu eepesenti abantu bonke achaphazeleka kuyo kube kanye ebomini babo. Kwiimeko ezininzi, kunzima. Ngokutsho koqikelelo olulondolozayo, i-1.0% yabemi baseYurophu ngoku banesifo se-urticaria esingapheliyo. Ngokungafaniyo nabantwana, ekungafunyanwanga kwimeko ethile yesini ye-urticaria (urticaria) ukuza kuthi ga ngoku, i-urticaria kubantu abadala ixhaphake kakhulu kubafazi. Ngokumalunga ne-urticaria engapheliyo, umyinge umalunga ne-2: 1. Abantu abaphakathi kweminyaka engama-30 ukuya kwengama-50 bahlala bechaphazeleka. Phakathi kwabantu abaneminyaka engama-70 ubudala okanye ngaphezulu, kwenzeka ngokungaqhelekanga. Ngokwahlukileyo, imingxunya kwiintsana ezisandul 'ukuzalwa, zihlala zihlala iintsuku nje ezimbalwa, aziqhelekanga.
I-Urticaria ibonakaliswa ngokuqala ngesiquphe kwamavili alumkileyo kunye / okanye i-angioedema. Ulusu lomzimba uphela okanye yinxalenye kuphela enokuchaphazeleka. Iivili zinokwenzeka kuphela ekuphenduleni inkuthazo ethile (umzekelo, ukubanda, uxinzelelo, okanye ukukhanya kwelanga) okanye ngokuzenzekelayo, okt, ngaphandle kwesizathu esithile.
Ivili lineempawu ezintathu eziqhelekileyo:
- ukudumba okungaphezulu kwesikhumba sobukhulu obahlukeneyo, phantse kuhlala kungqongwe bubomvu
- ukurhawuzelela okanye ukutshisa
- ukungazinzi - ukubonakala kolusu kuhlala kubuyela esiqhelweni ngaphakathi kweeyure eziyi-1-24.
Ngokwembonakalo yazo, la maqhuqhuva ayafana nokudumba kolusu okubangelwa ziinwele ezihlabayo zenettle (Lat. Urtica dioica). Indawo echaphazelekayo yesikhumba iyadumba kwaye ekuqaleni ibomvu kwaye kamva ibomvu ibomvu ibe mhlophe embindini kwaye ibomvu macala onke. Amavili abonakala eqhubeka ngamanye amaxesha okanye "efuduka". Olu luvo luvela kwinto yokuba ivili lomntu liyanyamalala, kodwa ecaleni kwalo kukho elitsha. Rhoqo kukho ukudumba okunzulu kwesikhumba-ekuthiwa yi-angioedema-ukongeza kwimingxuma (ngamanye amaxesha ngaphandle kwemingxuma).
I-Urticaria sesinye sezifo eziqhelekileyo zolusu. Kukwaziwa kananjalo phantsi kwegama lemingxuma okanye irhashalala. Phantse umntu omnye kwabane ufumana i-urticaria ngexesha lobomi bakhe. Uninzi lwezi ziqendu luhlala kuphela kwiintsuku okanye iiveki ezimbalwa kwaye alunangxaki. Oku kubizwa ngokuba yi-urticaria ebukhali. Eyona nto inzima ngakumbi (ukunyamezela nokunyanga) ngala matyala ahlala iinyanga okanye iminyaka (ngamanye amaxesha amashumi eminyaka). Igama livela kwi-nettle ehlabayo (Lat. Urticaria dioica okanye Urticaria urens, urere = burn) - ngokungathandabuzekiyo kuba ulusu lukhangeleka lwanjalo kwimeko yemingxunya ngokungathi umntu "utshisiwe" ngamarhawu.
Iimpawu ze-Urticaria
Ingxaki ukurhawuzelela
Ukurhawuzela yeyona ngxaki inkulu kwizigulana ezine-urticaria. Ngokukodwa ukurhawuzelela ebusuku kunokuba noxinzelelo olukhulu, kuba kuphazamisa ukulala, kwaye kubonisa uthintelo olukhulu kumgangatho wobomi.
Ukurhawuzelela kubaluleke kakhulu kwizigulana ezinengxaki yokubizwa ngokuba yi-urticaria factitia. Apha ukukrwela kunye nokuhlikihla ulusu kukhokelela ekubonakaleni kwemingxuma emitsha kunye nokuqhubela phambili ukurhawuzelela. Ukurhawuzela ulusu kancinci, umz. Ukurabha okungazi nto kolusu ngexesha lokulala kunokubangela uhlaselo oluqatha lokurhawuzelela.
Ukuvela ukurhawuzelela
Ukukhutshwa kwe-histamine kwiiseli zemasti kukhokelela ngqo ekurhawuzeleleni.
Izinto ezininzi zinokubangela ukurhawuzelela. Eyona nto ixhaphakileyo kwezi zinto kukuba ikhuphe i-neurotransmitter histamine kwinyama, edlala indima ephambili ekuvuseleleni ukurhawuzelela. Oko kubizwa ngokuba ziiseli zemasti zesistim somzimba sokuzikhusela kukhupha ii-neurotransmitters ezithile (ngakumbi i-histamine). Phantse yonke i-histamine eyenzeka kulusu igcinwe kwiiseli ezibizwa ngokuba yimast mast. Ukuba ezi seli zenziwe zasebenza, okt. Ngenxa yoko, ii-capillaries ziyanda, ulusu ludumba kwaye lube bomvu kwaye lurhawuzelele, kunye namavili.
Nangona kunjalo, i-histamine ikwavuselela imisonto yoluvo kulusu, ethi emva koko ikhuphe izinto ezithile ezibangela ukurhawuzelela (i-neuropeptides). Ezi neuropeptides azibangeli kuphela ukurhawuzelela kodwa zenze ukuba iiseli zemasti zisebenze, ukuze isangqa esikhohlakeleyo siqale, siphele kuphela xa kungekho iiseli zemasti kunye ne-nerves ezinokwenziwa zisebenze. Iiseli zeMast zibekwe ikakhulu kwindawo ekufuphi nemithambo yegazi kunye nemithambo-luvo. Ke ngoko, unxibelelwano phakathi kweeseli zemast, iiseli zemithambo, kunye nefayibha yentsimbi zilunge kakhulu.
Emva kokulunywa sisinambuzane okanye emva koqhakamshelwano namarhawu, siziva sisiphumo sokurhawuzelela i-histamine kakhulu. Ukongeza kwizinto ezikhupha i-histamine engapheliyo, ityhefu yezinambuzane ezininzi kunye neetyhefu eziveliswa zizityalo ezikhuthaza ukurhawuzelela ziqukethe i-histamine, engena kulusu kwaye iyicaphukise. Olu khuthazo lusibangela ukuba sikhuhle okanye sihlikihle ulusu kwaye luvumele igazi elininzi ukuba lifike kweli nqanaba, ukuze izinto ezicaphukisayo zisuswe ngokukhawuleza.
Yintoni enceda ekurhawuzeleleni?
Kwizigulana ukurhawuzelela kuhlala kuyingxaki enkulu kwaye kwehlisa umgangatho wobomi kakhulu. Kuya kufuneka uphephe ukukrwela, kwaye oku kulula ukutsho kunokwenza. “Ndingayeka njani ukukrwempa xa irhawuzelela?” kubuza isigulana.
- Gcina iinzipho zakho zinqunyulwe zimfutshane kakhulu, kwaye ubethe indawo ebetha ngokurhoxa (ngasentla) kwicala lesandla.
- Okupholisa kuphelisa ukurhawuzelela. Ungasebenzisa iipakethi ezipholileyo ozigcina kwifriji, kodwa ukuthatha ishawa epholileyo kwindawo ebandayo kunokuba luncedo kakhulu. Ukuba unesifo se-urticaria ebandayo, kuya kufuneka uphephe la manyathelo.
- Ukuvusa ikomityi yebicarbonate (umz. Umgubo wokubhaka) emanzini apholileyo okuhlamba kunye nokuhlamba imizuzu eli-10 kunokunciphisa ukurhawuzelela.
- Ukuhlikihla ulusu ngamanzi eviniga (icephe elinye leviniga kwilitha enye yamanzi) kunokuzisa isiqabu sexeshana.
- Izithambiso kunye neegel ziqukethe ii-antihistamines zidibanisa isiphumo se-antihistaminic yendawo kunye nefuthe lokupholisa.
- I-khrimu / into yokuthambisa ene-5% ukuya (ubuninzi) i-10% ye-polidocanol, ngokunokwenzeka ngokudibanisa i-urea, inokunciphisa ukurhawuzelela ngokufanelekileyo.
- Ukusetyenziswa kwe-anyanisi okanye amathontsi (amakhefu) akunakunceda.
- I-Cortisone oinments ayinampembelelo kurhawuzelelo.
Iimbangela ze-Urticaria
Eluswini, i-histamine, uxanduva lokurhawuzelela kunye ne-hives, kwenzeka kuphela kwiiseli zemast. Iimvumba zivela ngenxa yokuba izitya zesikhumba kwindawo yesikhumba echaphazelekayo ziqala ukuvuza. I-Histamine yenza iiseli zemithambo yegazi zihambe zisuka komnye nomnye ngokuzibophelela kwizakhiwo ezithile (i-histamine receptors) kwiiseli zemithambo-luvo kwaye ngaloo ndlela zibonisa iiseli zemithambo-luvo ukuba kufuneka zihambelane. Oku kuvumela ulwelo lwegazi kunye nezinye iiseli zegazi ukuba zibaleke ngaphakathi kwenqanawa ziye kwizicubu ezijikelezileyo. Ukongeza histamine, iimveliso mast cell ezifana iileukotrienes okanye ezinye izithunywa (ezibizwa ngokuba zii-cytokines) zinokunyusa ukugcwala kwemithambo yegazi. Iziphumo zeziyobisi ezichasayo xa urticaria inokuchazwa ngento yokuba la machiza athintela ngokukodwa ukubopha kwe-histamine kwii-histamine receptors. La machiza ke ngoko abizwa ngokuba zii-antihistamines. Inyaniso yokuba ii-antihistamines azincedi onke amatyala e-urticaria ibonisa ukuba i-histamine ayisiyiyo kuphela i-itch- kunye nemingxunya yokunciphisa indalo edlala indima apha.
Zisebenza njani iiseli zemasti ngokunxulumene neendidi ezahlukeneyo zeurticaria?
Lo mbuzo ungaphendulwa ngokulula ngokubhekisele kwi-urticaria ye-aleji, uhlobo olunqabileyo lwe-urticaria engapheliyo. Iseli yemasti yeyona nto iphambili ekulweni nokwaliwa komzimba kwaye iyabandakanyeka kuzo zonke izinto ezaliwa ngumzimba yi-protein ye-immunoglobulin E (IgE) yiyo ke enoxanduva lweempawu i-asthma, hay fever, okanye Eczema. Iihives zinokubangela i-allergic mast cell activation, oko kukuthi, i-activation ye-IgE kunye ne-allergen (into enokuthi ibangele ukusabela komzimba). Kwimeko enjalo, izinto eziguquguqukayo zingena emzimbeni kunye nokutya okanye umoya ophefumlwayo (umzekelo, umungu womthi, umungu wengca, inkunkuma yendlu yothuli) emva koko ivule iiseli zemast, ezilayishwe izilwa-buhlungu ze-IgE ezihambelanayo. Kunqabile ukuba ukufunxwa kokutya okuhlanganayo kunokubangela i-urticaria nakwimeko zokwaliwa okunjalo.
Nawuphi na umntu unokuba ayidibani ngexesha lakhe okanye lobomi bakhe. Oku kwenzeka ukuba siyakhuthazeka ngokuchasene nomungu othile njenge-birch pollen emva koqhakamshelwano nomungu. Ubuntununtunu bubhekisa kwimveliso ye-immunoglobulins (anti-protein) ngokuchasene nento ethile, kumzekelo wethu ngokuchasene ne-birch pollen. Ukuba sivuselelwe, imizimba yethu ivelisa ii-immunoglobulins ezahlukeneyo ezinemisebenzi eyahlukeneyo. Uhlobo lwe-E immunoglobulins (IgEs) olwenziwe ziiseli ezikhuselayo zamajoni omzimba, umzekelo, ziyabambeka kwiindawo ezilungiselelwe ngokukodwa kwiiseli zemasti (ii-receptors ze-IgE) xa zidlula emzimbeni womntu. Ngoku, xa imizimba yethu iphinda inxibelelana ne-birch pollen, ii-IgEs ezibambelela kwii-IgE receptors ezikwiiseli zemasti ziyayiqonda impova kunye nokuziqokelela. Iseli yemasti apho i-IgE ine-pollen ye-birch evalelweyo iyasebenza kwaye ikhupha i-histamine yayo. Ukuphikiswa komzimba kuyenzeka. Le ndlela ifundwe kakuhle yokusebenza kweeselfowuni ifunyanwa kuphela kwinxalenye encinci yazo zonke izigulana ze-urticaria.
Ngokuphindaphindiweyo ukwenziwa kwee-antibodies (imizimba yokukhusela iiproteni) ngokuchasene ne-IgE receptor okanye i-IgE eboshwe kuyo kubonakala ngathi inoxanduva lwe-urticaria. Ukuya kuthi ga kwiipesenti ezingama-30 zezigulana ezine-urticaria ezingapheliyo, ii-antibodies ezichasene nezinto zomzimba zinokufunyanwa. Ngamanye amagama, umzimba uyazichasa. Ke ngoko, omnye uthetha ngee-autoantibodies kunye I-urticaria yokuzimela. Uvavanyo olulula lobukho be-urticaria yokuzimela komzimba kukujova igazi lesigulana, okanye ulwelo lwegazi, kulusu lwengalo. Kwizigulana ezine-antibodies ngokuchasene ne-IgE receptor yazo okanye i-IgE, oku kukhokelela ekwakhekeni kwamavili abalulekileyo.
Inkqubo yokuncedisa yinto ebalulekileyo kuthungelwano lomzimba lokhuselo lomzimba. Uxanduva lwayo oluphambili lubandakanya ukutshatyalaliswa ngokuthe ngqo kweeseli kunye neearhente (ezinje ngeentsholongwane okanye iiparasites) kunye nokusebenza kwenkqubo yomzimba yokuzikhusela. Ukusebenza kwenkqubo yokuncedisa, umzekelo, kwimeko yosulelo lwebhakteria, kukhokelela ekukhululweni kwezinto ezinamandla ezisebenzayo zeseli. Rhoqo, urticaria enganyangekiyo ibangelwe lusulelo olungapheliyo (umz. Urticaria engapheliyo. Oku kubizwa urticaria ngenxa yosulelo.
Igama elithile ukunganyamezelani urticaria isetyenziswe kwiimeko apho umzimba awukwazi ukunyamezela into ethile. Ukungonwabi kwenzeka ngenxa yokunganyamezeli izinto ezifana namayeza, izigcina-lwazi, okanye idayi ekutyeni. Ukuphepha into ebangela ukuba umntu aqale, umz. ngokutya, kunokuzisa impiliso.
Ukuxilongwa kwe-Urticaria
Lungiselela udliwano-ndlebe nogqirha wakho malunga ne-urticaria ngokulandela la manyathelo:
- Qaphela xa i-urticaria yakho yenzeka okokuqala kwaye kaninzi kangakanani ukungakhululeki kwenzeke ukususela ngoko.
- Ucinga ukuba yintoni unobangela? Ngaba zikho izinto ezenza mandundu i-urticaria yakho?
- Bhala phantsi unyango lwakho lwangaphambili (igama, ubude, idosi).
- Bhala phantsi amayeza owathathayo ngokuchasene ne-urticaria ukuza kuthi ga ngoku (igama leziyobisi, ixesha lokusetyenziswa, idosi).
- Aye anceda kangakanani la mayeza, ibe yiyiphi imiphumo ebenayo?
- Bhala phantsi amayeza owathathayo ngoku, kwanalawo awathathwanga ngenxa ye-urticaria okanye angamiselwanga ngugqirha wakho.
- Nceda urekhode amayeza ongawasebenzisi rhoqo (umz. iipilisi zentloko) kwaye uchaze ukuba kangaphi ngenyanga ulisela iyeza kunye nokuba ugqibele nini ukulisebenzisa.
- Ukuba uvavanyo sele lwenziwe ukufumana unobangela wemingxuma yakho, yiza neziphumo zangaphambili.
Ifoto yotshintsho lolusu lwakho
Ngexesha leefowuni eziphathwayo, oko kufuneka kube lula.
Kwizigulane ezininzi, amavili akwenzeki yonke imihla. Ke kufuneka ulindele ukuba awukwazi ukubonisa ugqirha wakho ukuba imeko yesikhumba sakho ngexesha loqhambuko ibonakala njani.
Xa ufota izilonda, zinonophele ukuze zivele njengoko besenza. Iimeko zokukhanyisa ezilungileyo (ukukhanya kwemini, ukukhanya, ukukhanya kwe-neon), umgama owaneleyo (ubuncinci i-30 cm), kunye nemvelaphi emnyama iluncedo apha.
Unyango lwe-Urticaria
Unyango ngamayeza lwenziwa ngendlela efanayo ngokunxulumene nawo onke amatyala e-urticaria engapheliyo.
Ngokuhambelana nenkqubo yamanqanaba amathathu, amayeza alandelayo asetyenziswa.
- Antihistamines
- Abachasi beLeukotriene
- ICyclosporin A
- Omalizumab (entsha kunyango)
Antihistamines
La machiza, aphikisana nefuthe le-histamine kwaye aziwa kakhulu kubantu abanengxaki yokungezwani komzimba, asetyenziswa kuqala. Ekuqaleni, idosi elula yemihla ngemihla iyacetyiswa, njengoko isetyenziswa rhoqo ngokunxulumene nezigulana ezaliwa. Oku kuyahambelana, umzekelo, ukuya kwi-5 mg ye-levocetirizine okanye i-desloratadine okanye i-10 mg cetirizine okanye i-loratadine okanye i-20 mg ye-bilastine okanye i-180 mg ye-fexofenadine. Ukuba, emva kweeveki ezimbini zolawulo oluqhubekayo lwe-antihistamine, kusekho ukungahambi kakuhle, amayeza edosi ephezulu kakhulu anokukhutshwa ngugqirha. Ukuya kumaxesha amane oko kuchazwe kwiphetshana lepakethe njengedosi yesiqhelo. Oku akuyongozi. Nangona kunjalo, iidosi eziphezulu zibangela ukudinwa okanye ukulala kwabanye abantu.
Malunga nesibini kwisithathu sabo bonke abaguli be-urticaria banokuhlala kakuhle nesifo kunye ne-antihistamines kunye nezinye iindlela ezingezizo ezamayeza. Nangona kunjalo, ezinye iindlela ziyafumaneka kwisithathu esisele.
Abachasi beLeukotriene
Ileukotrienes zizithunywa zemichiza ezenziweyo ngokunxulumene nokudumba kwaye zidlala indima kuphuhliso lweempawu zesifuba ezifana nokudumba kunye nokunciphisa iindlela zomoya. Eli chiza, nalo, ke ngoko lisetyenziselwa ikakhulu i-asthmatics, kodwa liyasebenza nasekunyangeni ezinye zezigulana ze-urticaria.
Abachasi beLeukotriene abanjengeMontelukast baphucula iziphumo ze-leukotrienes ezinokuthintela ukudumba. Nangona kunjalo, zithathwa njengezisebenza kancinci kunee-antihistamines.
ICyclosporin A
ICyclosporin A icinezela amajoni omzimba kwaye ke ziiseli zemasti. Isetyenziselwa i-psoriasis eqatha, isifo se-atopic dermatitis okanye isifo esinganyangekiyo samathambo / isifo samathambo. Ingabangela-ngamanye amaxesha imiphumo emibi-kwaye ke unyango kufuneka lujongwe ngokukhawuleza.
Omalizumab
Iyeza elitsha yi-omalizumab. Eli chiza, nalo, ekuqaleni laphuhliswa ukunyanga isifuba. Ukusebenza kwayo ngokuchasene ne-urticaria kwafunyanwa ngengozi. I-Omalizumab ayithathwa njengecwecwe kodwa ifakwe ngaphakathi kolusu. I-Omalizumab iyasebenza ngokuchasene ne-immunoglobulin E (IgE). Ngokwenyani, le immunoglobulin-ubuncinci oku bekukholelwa ukuza kuthi ga ngoku-idlala indima encinci kwindidi ezininzi ze-urticaria. Nangona kunjalo, kuyaziwa ukuba kwimeko yezigulana ezigulayo i-IgE idlala indima ebaluleke kakhulu ekusebenzeni kweeseli zemasti. Ngokufanelekileyo, ukuvalwa kwe-IgE yi-omalizumab kuthintela nje ukusebenza kweeseli zemasti okanye "i-cascade", ekhokelela kwimingxunya emininzi kunye ne-angioedema.
Zininzi izifundo zeklinikhi ezibonisa ukuba i-omalizumab ilungile kwaye ikhuselekile kodwa ngaphezulu kwayo yonke le nto ihlala isebenza ngokukhawuleza okukhulu. Ukuba ukungaphatheki kakuhle akunakulawulwa ngale rejimeni ngexesha elifutshane, i-cortisone inokulawulwa njengecwecwe okanye inaliti. Esi sisombululo kufuneka sisetyenziswe njengonyango olunye okanye njengonyango lwexesha elifutshane. Unyango olusisigxina kunye ne-cortisone ayifanelekanga ngokunxulumene ne-urticaria.
Ezinye iindlela
Iindlela zovavanyo zibandakanya, umzekelo, unyango lweempawu kunye neeprobiotic, oko kubizwa ngokuba lonyango lwe-histamine habituation (kunye ne-histaglobin), inaliti yegazi elipheleleyo, kunye ne-acupuncture.
Ikhithi engxamisekileyo
Kwiimeko ze-urticaria enganyangekiyo, umz. Kwiimeko apho kukho ukudumba kwe-mucosal okubangela ubunzima bokuginya kunye nokuphelelwa ngumphefumlo, ukuhlala uthwele into ebizwa ngokuba yixakeka likaxakeka apho kuhlaselwa i-urticaria ngamandla kunokucetyiswa. Uninzi lwezixhobo zongxamiseko zinokulungiselela ukusebenza ngokukhawuleza kwe-cortisone kunye ne-antihistamine.
Yintoni enokuyenza kwisigulana i-Urticaria?
Elona nyathelo libaluleke kakhulu kukuchonga izinto ezibangela i-Urticaria kunye nokuchonga umqobo ngamnye. Emva koko, i-trigger kufuneka ithintelwe ukuya kuthi ga kwinqanaba elinokwenzeka. Qhubeka nedayari yakho ukubhala ngokuchanekileyo ikhosi yesi sifo. Uhlaselo oluncinci okanye ukuncipha kobukhali bohlaselo sele kuyimpumelelo.
Ngokunxulumene nabanye Iifom ze-urticaria, Ukuhlala ngokufana ne-immunotherapy esetyenziswa ngokunxulumene nezigulana ezichasayo kunokwenzeka. Ngokuyinxenye oku kungenxa yokuba iiseli zemasti, xa zikhuphe i-histamine yazo, zithatha ithutyana zide zisebenze kwixesha elizayo. Abanye abaguli bayakuxhaphaza oku ngabom.
Umzekelo, ibhafu ebandayo yemihla ngemihla (yengalo) inokubangela ukuba iimpawu ezibandayo ze-urticaria zinyamalale usuku lonke okanye ubuncinci ukunciphisa ezi mpawu. Umntu ophendula kuxinzelelo ngamavili anokubangela amavili ngabom ngokusebenzisa ukukhuhla okanye uxinzelelo ngaphambi kwemeko yoxinzelelo efana noviwo okanye udliwanondlebe lomsebenzi ukuze angabikho kurhawuzelelwa kwimeko yoxinzelelo kamva. Kodwa nceda uxoxe ngala manyathelo nogqirha, kuba iimpendulo ziyahluka kakhulu kwaye akukho mntu kufuneka athathe umngcipheko wokuphendula ngobundlobongela ukuba akukho ncedo lukhona.
Uxinzelelo, ngasendleleni, luhlala lubangela okanye ukukhulisa i-urticaria. Kuyinyani ukuba “thintela uxinzelelo” kulula ukutsho kunokuba ukwenzile. Kwakhona, ukugcina idayari kuya kukunceda uchonge uxinzelelo lwe-urticaria. Ukufunda iindlela zokuphumla okanye uqeqesho lwe-autogenic kunokunceda.
Gwema ukuthatha ii-NSAID (iziyobisi ezingekho-steroidal ezichasayo). Oku kubandakanya, umzekelo, i-acetylsalicylic acid (kwi-aspirin, Thomapyrin njl.njl.), I-diclofenac, ibuprofen, phenylbutazone. Ukuthatha idosi enye yala machiza kunokubangela ukuhlaselwa.
Ngakumbi phepha iziselo ezinxilisayo. Utywala bunokucaphukisa ulwelwesi lwesisu ukuze ii-enzymes ezithile zendlela yesisu (i-diamine oxidases) eziyimfuneko ekonakalisweni kwe-histamine azisakwazi ukwaphula i-histamine efakwe ngokutya ngokwaneleyo.
Imbali emva koko ifakwa egazini nge-mucosa yamathumbu amancinci kwaye inokubangela i-urticaria kunye ukungonwabi okunxulumene noko. Utywala bunokubangela ukuba iiseli zemasti, ezona zinto zibangela iiseli ze-urticaria, zisebenze ngokulula.
Ukutya okunezinongo nako kunokubacaphukisa inwebu yangaphakathi kwaye ke kuhlala kunganyamezeleki kakuhle kwaye kufuneka kuthintelwe zizigulana ze-urticaria.
Resources
Isigulana kunye neFlyer yeCU yoSapho
Isishwankathelo soMqulu we-CU weSigulana
Izixhobo ezifanelekileyo
www.dermnetnz.org/reactions/urticaria.html