I-GAAPP Co-authored Publications
Short courses of adjunctive systemic corticosteroids are commonly used to treat acute urticaria and chronic urticaria flares (both with or without mast cell-mediated angioedema), but their benefits and harms are unclear. Systemic corticosteroids for acute urticaria or chronic urticaria exacerbations likely improve urticaria, depending on antihistamine-responsiveness, but also likely increase adverse effects in approximately 15% more.
Funda upapasho: https://www.jaci-inpractice.org/article/S2213-2198(24)00400-8/fulltext
Inkqubo yokufikelela eluntwini yehlise ukusetyenziswa kwezibonelelo zempilo phakathi kwabantwana abasengozini enkulu yesifuba eTennessee ngokujolisa imiqobo ethile kukhathalelo, ngokwengxelo epapashwe Izibhengezo ze-Allergy, i-Asthma kunye ne-Immunology. Izigulane ezithathe inxaxheba kule nkqubo zafumana olu phuculo kunyaka wokubhalisa, uChristie F. Michael, MD, unjingalwazi onxulumeneyo kwisebe lezifo zabantwana kwiYunivesithi yaseTennessee Health Science Centre, kunye noogxa babhala kwingxelo.
Funda upapasho: https://www.healio.com/news/allergy-asthma/20240119/outreach-program-decreases-health-care-resource-use-among-children-with-asthma
I-urticaria engapheliyo (CU) kuphuhliso oluqhubekayo lwamavili (aka '' hives '' okanye '' welts ''), i-angioedema, okanye zombini iiveki ezingaphezu kwe-6. Ukujikeleza kunye ne-angioedema zenzeke ngaphandle kwezinto ezibangela ukuba i-urticaria engapheliyo kwaye iphendule kwizinto ezaziwayo neziqinisekileyo ezibangela umzimba kwi-urticaria engapheliyo. Malunga ne-1.4% yabantu kwihlabathi liphela baya kuba neCU ngexesha lokuphila kwabo. Intsebenziswano yezigulane, ababoneleli, imibutho ekhuthazayo, kunye nabameli bamayeza baye benza i-charter yesigulane ukuchaza imigaqo yokunyamekela eyinyani kunye nokufezekiswa ukuba izigulane ezine-CU kufuneka zilindele ukufumana.
Funda upapasho: https://link.springer.com/content/pdf/10.1007/s12325-023-02724-6.pdf
Umbefu wabantwana ufuna inoveli yovavanyo lweziphumo zonyango (COAs) eziphuhliswe ngokwe-US Food and Drug Administration's (FDA's) isikhokelo solawulo sokuvavanya inzuzo yonyango kulingo zonyango. Ukujongana nesi sikhewu, iQela eliSebenzayo le-Asthma ye-Asthma yeSigulane (PRO) ye-Consortium's Pediatric Working Group liye laqhubeka nokuphuhliswa kwe-2 COAs ukuvavanya iimpawu ze-asthma kunye neempawu kwiimvavanyo zekliniki ze-asthma zabantwana ukuxhasa isiphelo sokuphumelela.
Funda upapasho: https://jpro.springeropen.com/counter/pdf/10.1186/s41687-023-00639-y.pdf
Injongo yolu phononongo yayikukuvavanya ukusetyenziswa kokuxilonga kwekhithi yovavanyo enoveli enokuthi ibone zonke iiserogroups zethiyori. Legionella pneumophila yokufumanisa isifo legionella inyumoniya, xa kuthelekiswa nezixhobo ezikhoyo.
Funda upapasho: https://www.sciencedirect.com/science/article/pii/S1201971220323122
Iqela labaphandi bamazwe ngamazwe liphuhlise i-International Collaborative Asthma Network (ICAN) ngenjongo yokwabelana ngophando olutsha kwiindlela zesifo, ukuphuhlisa ubugcisa obutsha kunye nonyango, ukuququzelela izifundo zokulingwa kunye nokubandakanya abaphandi bemisebenzi abakwinqanaba lokuqala abavela kwihlabathi lonke. Le ngxelo ichaza injongo, uphuhliso kunye neziphumo zeforam yokuqala ye-ICAN.
Funda upapasho: https://pubmed.ncbi.nlm.nih.gov/37260461/
Sichonge izinto ezine ezisekelwe kubungqina obunobungqina bokuphononongwa ngaphambi kokukhutshwa kwesigulane esibhedlele, kubandakanywa (1) ukuyeka ukutshaya kunye novavanyo lokuvezwa kwendalo, (2) ukulungiswa kwonyango, (3) ukuvuselelwa kwemiphunga, kunye (4) nokuqhubeka kokunyamekela. .
Funda upapasho: https://link.springer.com/article/10.1007/s12325-023-02609-8
Ukuqondwa kakubi kwe-EAD yi-HCPs kaninzi kuba negalelo ekuxilongeni ukulibaziseka, ukulibazisa ngakumbi ukufikelela kwesigulane kukhathalelo olufanelekileyo kunye nonyango olusebenzayo kunye neziphumo zempilo ezimbi. Lo mqulu ujolise ekuchazeni amalungelo angundoqo ezigulane kunye nezinto ezilindelekileyo malunga nokulawulwa kweemeko zabo kunye nokumisela isicwangciso sesenzo esinqwenelekayo sokuphucula iziphumo zempilo kwizigulane ezine-EADs.
Funda upapasho: https://pubmed.ncbi.nlm.nih.gov/35489014/
Isifuba sombefu sichaphazela abantu abazizigidi ezingama-339 kwihlabathi jikelele, kuqikelelwa ukuba yi-5-10% ye-asthma enzima kakhulu. Kwiimeko ezingxamisekileyo, i-corticosteroids yomlomo (OCS) inokusindisa ubomi, kodwa unyango olunzima kunye nexesha elide lunokuvelisa iziphumo ezibi kakhulu zeklinikhi kunye nokwandisa umngcipheko wokufa. Ngoko ke, izikhokelo zehlabathi zincoma ukunciphisa ukusetyenziswa kwe-OCS.
Funda upapasho: https://link.springer.com/article/10.1007/s12325-023-02479-0
Amaxabiso esigulane kunye nezinto ezikhethwayo zinokuzisa ukhathalelo lwe-atopic dermatitis (AD). Izishwankathelo ezicwangcisiweyo zobungqina obujongene nexabiso lezigulane kunye nezinto ezikhethwayo azizange zifumaneke ngaphambili. Injongo kukwazisa i-American Academy of Allergy, Asthma & Immunology (AAAAI)/American College of Allergy, Asthma and Immunology (ACAAI) Joint Task Force on Practice Parameters uphuhliso lwesikhokelo se-AD, izigulane kunye nomnakekeli kunye nezinto ezikhethwayo kulawulo lwe-AD. zenziwa ngokucwangcisiweyo.
Funda upapasho: https://jamanetwork.com/journals/jamadermatology/article-abstract/2800632
Ukufikelela kumayeza okuphefumla afikelelekayo ezifo ezingapheliyo zokuphefumla (CRDs) kuthintelwe kakhulu kumazwe anengeniso ephantsi kunye nephakathi (LMICs), ebangela ukugula okuthintelekayo kunye nokufa. Kukho amathuba okufumana ukufikelela okuphuculweyo kumayeza arholileyo afikelelekayo, aqinisekisiweyo ngomgangatho kwii-LMICs ngolungelelwaniso, amaqela achaphazelekayo amaninzi, iinzame zentsebenziswano.
Funda upapasho: https://www.ingentaconnect.com/contentone/iuatld/ijtld/2022/00000026/00000011/art00006
Ukuthengwa kwe-2021 yenkampani yokuphefumula yokuphefumula i-Vectura nguPhillip Morris International iye yagxekwa yimpilo yoluntu kunye noluntu lwezonyango, njengengxabano yomdla, kunye negalelo elincinci ukuza kuthi ga ngoku, ukusuka kuluntu lwesigulane okanye kuluntu.
Funda uPapasho: https://thorax.bmj.com/content/early/2022/07/14/thorax-2022-219142
Ezi nkcazo ezisemgangathweni ezisemgangathweni zigxininisa izinto ezingundoqo zokunakekelwa kweCOPD, kubandakanywa ukuxilongwa, isigulane esaneleyo kunye nemfundo yomnakekeli, ukufikelela kunyango lwezonyango kunye nonyango olungekho semthethweni oluhambelana neengcebiso zamva nje ezisekelwe kubungqina kunye nolawulo olufanelekileyo yingcali yokuphefumula xa kufuneka, ulawulo olufanelekileyo lwe-acute. I-COPD exacerbations, kunye nesigulane esiqhelekileyo kunye nomnakekeli wokulandelela ukuphononongwa kwesicwangciso sokhathalelo.
Funda uPapasho: https://link.springer.com/article/10.1007/s12325-022-02137-x
Umbefu sesinye sezona zifo zixhaphakileyo ezingapheliyo ezilawulwa ngabongikazi besikolo, kwaye ulawulo lwaso luhlala lubandakanya ulawulo lweebronchodilators ezihanjiswa ngemitha yedosi yokuphefumla (MDI). Ukusetyenziswa kwe-MDI kufuna ulungelelwaniso kunye nolawulo lwamanyathelo ekufuneka enziwe ngokuchanekileyo nangokulandelelana kwawo. La manyathelo aphuculwe kakhulu, ngakumbi kubantwana babantwana, ngokusetyenziswa kwezixhobo zonyango-i-spacers kunye namagumbi okubamba i-valve. Injongo yeli nqaku kuphonononga ingqiqo kunye neziphumo zokusetyenziswa kwezi zixhobo kwimeko yesikolo.
Funda uPapasho: https://journals.sagepub.com/doi/10.1177/1942602X16646593
Oosokhemesti lilungu elixabisekileyo leqela lentsebenziswano elikhokelwa ngugqirha. Uphando loosokhemesti olwenziwa yiNethiwekhi ye-Allergy & Asthma lubonise ukuba oosokhemesti banokubonelela ngemfundo yesigulana esinexabiso ngobuchule obufanelekileyo kunye nesenzo samayeza ombefu ofulelweyo ngaphakathi kwesakhelo seNkqubo yeSizwe yeMfundo noThintelo loMbefu (NAEPP).
Read the Publication: https://www.jacionline.org/article/S0091-6749(16)32456-3/fulltext
Ukwenziwa kwezigqibo ekwabelwana ngako (SDM) kuya kuthandwa kakhulu kwaye kusetyenziswe kunyango njengendlela yokuxhobisa izigulane ezijongene neemeko ezikhethiweyo zonyango, ezifana ne-rhinitis ye-allergic, i-atopic dermatitis, i-allergies yokutya, kunye ne-asthma eqhubekayo. Injongo yolu hlaziyo kukufundisa umboneleli wezempilo ongalungelelaniyo malunga nendlela iSDM esebenza ngayo kunye nokubonelela ngeengcebiso ezisebenzayo kunye nezixhobo ze-SDM ze-allergist.
Read the Publication: https://www.annallergy.org/article/S1081-1206(18)30710-5/fulltext
Apha sibonelela ngePhepha leSigulane se-asthma enzima, equka imigaqo emithandathu engundoqo, ukudibanisa oorhulumente belizwe, ababoneleli bezempilo, abenzi bomgaqo-nkqubo abahlawulayo, amaqabane oshishino lwezempilo yemiphunga, kunye nezigulane / abanakekeli ukujongana nesidingo esingafezekanga kunye nomthwalo kwi-asthma enzima kwaye ekugqibeleni basebenze. kunye ukuhambisa uphuculo olunentsingiselo kukhathalelo.
Funda uPapasho: https://link.springer.com/article/10.1007/s12325-018-0777-y
I-urticaria engapheliyo ingumceli mngeni ekulawuleni kwaye ichaphazela kakhulu umgangatho wobomi. Le US, non-interventional qualitative study ivavanye uhambo lwezonyango lwezigulane kunye nomthwalo weemvakalelo ukusuka kwimpawu zokuqala ngolawulo lwesifo. Izigulana ze-urticaria ezingapheliyo zithathe inxaxheba kudliwano-ndlebe kunye needayari ezigqityiweyo ezigxile kwisifo kunye nembali yonyango / iimbono, impembelelo kubomi bomntu / bentsapho, kunye nobudlelwane noogqirha / abanye ababoneleli bezempilo. Kwadliwan’ indlebe noogqirha ngeembono zabo ngolawulo lwezifo nokunyanyekelwa kwezigulana.
Funda uPapasho: https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-3282
Ukwenziwa kwezigqibo ekwabelwana ngako (SDM) kuya kuthandwa kakhulu kwaye kusetyenziswe kunyango njengendlela yokuxhobisa izigulane ezijongene neemeko ezikhethiweyo zonyango, ezifana ne-rhinitis ye-allergic, i-atopic dermatitis, i-allergies yokutya, kunye ne-asthma eqhubekayo. Injongo yolu hlaziyo kukufundisa umboneleli wezempilo ongalungelelaniyo malunga nendlela iSDM esebenza ngayo kunye nokubonelela ngeengcebiso ezisebenzayo kunye nezixhobo ze-SDM ze-allergist.
Funda uPapasho: https://linkinghub.elsevier.com/retrieve/pii/S1081120618307105
Nangona isifo sombefu esiqatha sinokubeka ubomi esichengeni, izigulane ezininzi azizazi ukuba banale meko. Ukuqonda isigulana okuKhokela kuVavanyo lweSifo sombefu esiMandundu (i-PULSAR) yinoveli, iqela elisebenzayo lezinto ezininzi elijolise ekuphuhliseni nasekusasazeni inkcazo yehlabathi, egxile kwisigulane sesifuba esinzima ukuphucula ukuqonda kwesigulana sesifuba esinzima kunye nokwenza utshintsho kwindlela yokuziphatha kwesigulana apho izigulane ziyakhuthazwa ukuba zindwendwele iingcali zabo zezempilo, xa kufanelekile.
Funda uPapasho: https://link.springer.com/article/10.1007/s40271-019-00371-0
I-NHLBI ibambe iworkshop yoCwangciso lweSicwangciso soPhando seSifo soMbefu kwi-2014 ukunceda ukukhawulezisa ukuguqulelwa kwezinto ezintsha ezifunyenweyo kukhathalelo lwezigulane ezine-asthma ezinzima. Iworkshop ibize abaphandi ukuba bakhe kwinkqubela phambili yamva nje yetekhnoloji kunye ne-asthma pathobiology ukuphucula ulawulo olubi lwe-asthma, usebenzisa ungenelelo oluchanekileyo lokuphucula iziphumo zesigulane kunye nokunciphisa umthwalo wezempilo yoluntu we-asthma.
Funda uPapasho: https://www.atsjournals.org/doi/10.1164/rccm.201809-1817PP#_i1
Ukwenziwa kwezigqibo ekwabelwana ngazo (SDM) yinkqubo apho izigulane kunye nomboneleli wabo wezonyango bahlola ngokufanayo iinjongo zonyango, umngcipheko / inzuzo, kunye neendlela zonyango malunga nokhathalelo lwezonyango. Uncedo kwizigqibo zizixhobo ezinceda kwinkqubo yokucaciswa kwemilinganiselo kunye nokunceda ukuhlola iimfuno zezigqibo kunye neengxabano ezinokuthi zibekho. Injongo yolu phononongo yayikukuphuhlisa kunye nokuvavanya ukwamkeleka koncedo lwesigqibo kunyango lorhwebo lwamandongomane olukwalana.
Isifuba somoya wabantwana sihlala singumceli mngeni kwimpilo yoluntu enempembelelo enkulu kwihlabathi liphela. Injongo yolu phononongo yayikukubona kunye nokubeka phambili iimfuno zeklinikhi ezingafezekanga kwi-asthma yabantwana, engasetyenziselwa ukukhokela uphando lwexesha elizayo kunye nemisebenzi yomgaqo-nkqubo.
Read the publication: https://www.jaci-inpractice.org/article/S2213-2198(20)30147-1/fulltext
Njengabaxhasi bezigulane zehlabathi jikelele, siye saqulunqa lo mqulu wesigulane ukubeka umgangatho wokunyamekela abantu abahlala neCOPD kufuneka balindele, ukuphakamisa ulwazi kunye nokuqonda izizathu kunye nemiphumo yeCOPD kunye nokukwazi ukuphucula ukunakekelwa kwesigulane. Izigulana ezineCOPD kufuneka zixhotyiswe ukuba ziphile owona mgangatho uphezulu wobomi obunokwenzeka kunye nelona nani lincinci lokuqhambuka. Sibeka imigaqo emithandathu ngokuhambelana neziphakamiso zesikhokelo zangoku zeCOPD, ekufuneka ziphunyezwe ngoorhulumente, ababoneleli bezempilo, abenzi bomgaqo-nkqubo, amaqabane amashishini ezempilo yemiphunga kunye nezigulane / abanakekeli baqhubele phambili utshintsho olunentsingiselo kukhathalelo lweCOPD.
Funda upapasho: https://link.springer.com/article/10.1007/s12325-020-01577-7#Abs1
Nangona kuphela i-10% yezigulane ezine-asthma zinesifo esibi kakhulu, ezi zigulana zisebenzisa ukuya kwisiqingatha sazo zonke izixhobo zempilo ezisetyenziselwa ukunyanga isifo sombefu. Kwisigulana, isifo sombefu esiqatha sinxulunyaniswa nokugula kakhulu, ukonyuka komngcipheko wokufa, kunye nomgangatho ophantsi wobomi. Unyango olusebenzayo lwesifuba esimandla luyafumaneka, kodwa ukufikelela kolu nyango kuyahluka kwizigulana ezininzi kwihlabathi jikelele, kwaye azisoloko zisetyenziswa kakuhle xa zikhoyo.
Funda upapasho: https://link.springer.com/article/10.1007/s12325-020-01450-7
Injongo yeli phepha kukubonelela ngesishwankathelo semiba ephambili ye-specialized dermatology nursing practice ekulawuleni izigulane ezine-atopic dermatitis ephakathi ukuya kwi-atopic enzima. Indima yeengcali zabongikazi besikhumba ekuxhaseni izigulana kunye nokukhuthaza ukuqonda isifo, imfundo kunye nokubambelela kunyango iyaqhubeka nokuvela. Njengoko iimpawu zokhathalelo olukhethekileyo zinokwazisa nabanye abasebenzi bobuhlengikazi kwiindawo ezininzi zokunyamekela, ukuphononongwa kwamacandelo abalulekileyo kuhlolwe. Uqwalaselo oluthiwe thaca luvela kumbono we-pan-European kwaye lumele imbono eqokelelweyo yeqela leengcali zoongikazi besikhumba, i-dermatologists kunye nabameli bezigulane ezilandela iingxoxo ezimbini zetafile.
Funda upapasho: https://bmcnurs.biomedcentral.com/articles/10.1186/s12912-020-00494-y
Isifuba sombefu esimandundu luhlobo olungephi lwesifuba esinokuba nzima ukusilawula, nto leyo ekhokelela kwimpembelelo ekhethekileyo kumgangatho wobomi bomntu. Injongo yale nqaku yophononongo kukuphonononga ukungahambi kakuhle kwemibono ye-asthma enzima phakathi kwabachaphazelekayo abahlukeneyo ukuchonga indlela yokunciphisa umthwalo kunye nokuphucula ukunikezelwa kokhathalelo.
Read the publication: https://www.worldallergyorganizationjournal.org/article/S1939-4551(20)30403-8/fulltext
Ukusetyenziswa kwe-Cannabis kwizigulane ezine-allergies / i-asthma, iqela elinomngcipheko ophezulu wemiphumo emibi kwi-cannabis, ayaziwa. Injongo yolu phononongo yayikukumisela iipatheni zokusetyenziswa kunye nezimo zengqondo malunga ne-cannabis kwizigulana ezinokwaliwa / umbefu.
Read the publication: https://www.annallergy.org/article/S1081-1206(21)00022-3/fulltext
Eyona njongo yolu phononongo yayikukuqhuba uvavanyo lweemfuno zokuqinisekisa ulwazi lweengcali kunye nabazali kunye nezimvo malunga nemfundo yokulawula isifo sombefu kubantwana abakhubazekileyo ngokwasemzimbeni nangokwengqondo (IDs). Enye injongo yayikukuqonda iimfuno zemfundo yabantwana abane-ID malunga ne-acute acute breathing syndrome i-coronavirus 2 (SARS-CoV-2; coronavirus) kunye nezinye izifo ezosulelayo.
Funda upapasho: https://www.tandfonline.com/doi/abs/10.1080/02770903.2021.1878534?journalCode=ijas20
Kukho imfuneko yokunciphisa ukusetyenziswa kwe-corticosteroid yomlomo (OCS) kwizigulane ezine-asthma ukukhusela iziphumo zabo ezibi kunye nomthwalo onzima. Izikhokelo zangoku aziboneleli ngeengcebiso ze-OCS kwi-tapering kwizigulane ezine-asthma. Injongo yeli phepha yayikukuphuhlisa imvumelwano yobuchwephesha malunga nokucocwa kwe-OCS phakathi kweengcali zamazwe ngamazwe.
Funda upapasho: https://www.atsjournals.org/doi/10.1164/rccm.202007-2721OC
Abantu abane-rhinitis ye-alergic (AR) abangalawulwayo kunyango oluqhelekileyo banokunyangwa ngokusebenzisa i-alergy immunotherapy (AIT) elawulwa njengeepilisi, iinaliti okanye amathontsi. E-US, ukusetyenziswa kwe-sublingual immunotherapy njengeepilisi (SLIT-tablets) kulinganiselwe xa kuthelekiswa ne-subcutaneous immunotherapy (SCIT). Olu phononongo luphande ukhetho lwezigulane kwii-SLIT-tablets vs inyanga nenyanga okanye ngeveki ye-SCIT ngokwembono yesigulana sase-US.
Funda upapasho: https://www.dovepress.com/preference-for-immunotherapy-with-tablets-by-people-with-allergic-rhin-peer-reviewed-fulltext-article-PPA
Isifuba sombefu esimandundu luhlobo olungaphantsi lwesifo sombefu ekunokuba nzima ukusilawula, nto leyo ekhokelela kwimpembelelo ekhethekileyo kumgangatho wobomi bomntu. Injongo yale nqaku yophononongo kukuphonononga ukungahambi kakuhle kwemibono ye-asthma enzima phakathi kwabachaphazelekayo abahlukeneyo ukuchonga indlela yokunciphisa umthwalo kunye nokuphucula ukunikezelwa kokhathalelo.
Read the publication: https://www.worldallergyorganizationjournal.org/article/S1939-4551(20)30403-8/fulltext
Olu phononongo luvavanya ukuphindaphindeka kokuphefumla okubukhali kunye neentetho zefebrile ngexesha lamaza okuqala COVID-19 ubhubhani kwisifuba somntwana. Idatha evela kwiqela lezizwe ngezizwe le-PeARL ityhila impilo ephuculweyo kunye nomsebenzi wesifuba ngexesha lamaza okuqala COVIDUbhubhani we-19, mhlawumbi unxulunyaniswa nokwehla kokungakhuseleki kwizinto ezibangela isifo sombefu kunye nokwanda kokubambelela kunyango. Ngelo xesha, abantwana abane-asthma bafumana i-URTIs embalwa, iziqephu ze-pyrexia, ukutyelelwa ngokukhawuleza, ukungeniswa esibhedlele, ukuhlaselwa kwe-asthma, kunye nokulaliswa esibhedlele ngenxa ye-asthma, xa kuthelekiswa nonyaka owandulelayo.
Funda upapasho: https://www.atsjournals.org/doi/10.1164/rccm.202007-2721OC
Ukungafani phakathi kweempawu ze-asthma kunye ne-spirometry: iimpembelelo zokulawula isifo sombefu ebantwaneni.
I-Spirometry yenziwa kubantwana abangama-894 (5-19) e-Connecticut abathi kuvavanyo lweklinikhi bafumana isifuba se-asthma esiphakathi kwi-30% kunye nesifo se-asthma esingapheliyo kwi-32%, 33% kunye ne-5% ngokwahlukeneyo. Ukuphucula iiparamometri zeparameter kunxulunyaniswa nesifo esibi kakhulu seklinikhi. Kodwa uvavanyo lwe-spirometric lubonakalise ubukrakra besifo esingaphezulu kokuvavanywa kweklinikhi kwi-36% kunye nekhonkodensi phakathi kweziphumo ze-spirometric kunye neempawu zeklinikhi zazingalunganga, i-0.2 emva kohlengahlengiso lokhetho kunye nokuxhaphaka. Isifo se-asthma siyaziwa ukuba sincitshiswe ngonyango olufanelekileyo kwaye ababhali bacebisa ukuba iziphumo ze-spirometry zisenokuba sisikhokelo esingcono sezigqibo zonyango kuneempawu zempawu.
Schifano ED okqhubekayo. J Pediatr. 2014 Agasti 28. pii: S0022-3476 (14) 00650-7. ikhonkco: 10.1016 / j.jpeds.2014.07.026. [Epub phambi koshicilelo]
Funda upapasho: http://www.ncbi.nlm.nih.gov/pubmed/25175496
Ukutshaya kukaMakhulu xa ekhulelwe umama kunye nesifuba kumzukulwana: uMama waseNorway noMfundi oHlanganisa neQela.
Isifundo sase-Norwegian Mother and Child Cohort Study kubandakanya malunga ne-100,000 oomama nabantwana. Ukutshaya kukamakhulu xa ekhulelwe umama kwavavanywa ngokunxulumene neziphumo zesifuba kumzukulwana. Ngama-23.5% abantwana, oomama bathi oomama babo batshaya xa bekhulelwe. Isifo sombefu saxelwa kwi-5.7% yabantwana abangama-53,169 abanedatha yokulandelela kubudala beenyanga ezingama-36, kunye ne-5.1% yabantwana abangama-25,394 abanedatha kubudala beminyaka esi-7. 4.8. Kwakukho unxibelelwano oluqinisekileyo phakathi kokutshaya kukamakhulu xa ekhulelwe kunye nesifuba kuwo onke amaqela ama-45,607 abazukulwana, azimeleyo kwimeko yomama yokutshaya. Ngenxa yolwazi oluncinci malunga nemeko yezentlalo noqoqosho kunye nesifo se-asthma soomakhulu, izinto ezingafakwanga eziphazamisayo zinokubakho.
UMagnus MC okqhubekayo. Thorax. 2015 uJan 8. pii: thoraxjnl-2014-206438.
Funda upapasho: http://www.ncbi.nlm.nih.gov/pubmed/25572596
Ukuthembeka kunye nokusetyenziswa kwe-spirometry eyenziwa kubantu abane-asthma kwiikhemesti zoluntu.
Abaphandi base-Australia bavavanye idatha kwiiseshoni ze-2593 ze-spirometry ezenziwe ngoosokhemesti basekuhlaleni kwi-892 ye-asthmatics ngaphakathi kwezilingo ezimbini zokungenelela okukhulu kwe-asthma. Bekukho iimvavanyo ezintathu ezamkelekileyo kwi-68.5% yeeseshoni kunye novavanyo olunye olwamkelekileyo kwi-96%. Ukwamkeleka kwachazwa njengentlanganiso yemigaqo ye-ATS/ERS. Malunga nama-40% aneziphumo ezibonisa umqobo. Ngenxa yenkonzo, i-FEV1, kunye ne-FEV1/FVC yanda kakhulu kubathathi-nxaxheba bokufunda, njengoko kwenza ulawulo lwe-asthma. Abo bathunyelwa kooGqirha babeneziphumo ezibi kakhulu ze-spirometry. Ababhali bagqibe kwelokuba i-spirometry ngoosokhemesti inokuthenjwa kwaye iluncedo kuphononongo lwe-asthma yoluntu.
UBurton DL okqhubekayo. J Isifuba. Ngo-2015 uJan 7: 1-27
Funda upapasho: http://www.ncbi.nlm.nih.gov/pubmed/25563059
Ukusebenza kunye nokusebenza kwezitofu zokugonya zomkhuhlane wexesha kunye nobhubhane A (H1N1) 2009 kumazwe anengeniso ephantsi kunye nephakathi: uphononongo olucwangcisiweyo kunye nohlalutyo lwemeta.
Ugonyo lomkhuhlane luyacetyiswa kumazwe anengeniso ephantsi kunye nephakathi (ii-LICs kunye nee-MICs) kubantu abasengozini. Uphando kwi-3 yogcino-lwazi lwezonyango kumaphepha esiNgesi, isiFrentshi, iSpanish okanye isiPhuthukezi ngokusebenza kunye nempumelelo yesitofu sokugonya umkhuhlane kula mazwe ukususela ngo-1960-2011 luvelise izifundo ezingama-41. Kwii-MICs, isitofu sokugonya somkhuhlane sibonise ukusebenza okudityanisiweyo kwe-72% kunye ne-81% ye-1 kunye ne-2 yokulandelela unyaka kubantwana kunye ne-43% kunye ne-58% edibeneyo esebenzayo kwizitofu eziphilayo ezithotyiweyo kunye nezingasebenziyo ngokulandelelana kwabantu abadala. Isitofu sokugonya esingasebenziyo sinciphise iziphumo zentliziyo kwizigulana ezisemngciphekweni. Ukusebenza kwakufana noko kumazwe anengeniso ephezulu. Idatha yee-LICs kunye namanye amaqela asemngciphekweni kwii-MICs bezilinganiselwe.
UBreteler JK et al. Ugonyo. Ngo-2013 Oktobha 25; 31 (45): 5168-77. ikhonkco: 10.1016 / j.vaccine.2013.08.056. Epub 2013 Sep 5.
Funda upapasho: http://www.ncbi.nlm.nih.gov/pubmed/24012574
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