I-Angioedema livili lesikhumba elinzulu. Ngelixa kwimeko ye-hives, ulwelo luphuma kwiinqanawa phantsi kobuso besikhumba, "ukuvuza" kwi-angioedema kuluhlu olunzulu lwesikhumba.
I-Angioedema (i-angio = inqanawa, i-oedoema = ukugcinwa kwamanzi kwizicubu) ibonakaliswa ngu:
- ukudumba ngesiquphe, kakhulu kweengcamba ezinzulu zolusu
- maxa wambi iintlungu, kunqabile ukurhawuzelela
- ukubandakanyeka rhoqo kwiinwebu ze-mucous - ukuhlehliswa okuhlala ukuya kwiiyure ezingama-72 ixesha elide kune-hives.
Iqhuma elivelayo linomphetho ongacacanga kangako kwaye ngokufuthi awahlukani nolusu oluqhelekileyo ngombala. I-Angioedema idla ngokuvela kwindawo yobuso, ngakumbi malunga namehlo kunye nemilebe, kunye nezandla kunye neenyawo. Uninzi lokudumba, ngokwembono ebanzi, lunxulunyaniswa nokwaliwa kwaye lulamlwa yi-neurotransmitter histamine. Kodwa kukho nezinye izizathu ezingezo-alergic kunye ne-non-histamine-mediated zesikhumba kunye nokudumba kwe-mucosal.